| 000 -LEADER |
|---|
| fixed length control field |
02317cam a2200301 i 4500 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| ISBN |
9780071830935 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| ISBN |
0071830936 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| ISBN |
9789814670241 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| ISBN |
9814670243 |
| 082 00 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
615.7 |
| 100 ## - MAIN ENTRY--AUTHOR NAME |
|---|
| Personal name |
Shargel, Leon,(Acc.No:40017 Ref) |
| 245 00 - TITLE STATEMENT |
|---|
| Title |
Applied biopharmaceutics & pharmacokinetics / |
| 250 ## - EDITION STATEMENT |
|---|
| Edition statement |
Seventh edition. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Year of publication |
2016 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Number of Pages |
xvii, 910 pages : |
| Other physical details |
illustrations ; |
| 490 ## - SERIES STATEMENT |
|---|
| Series statement |
7th ed. |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Introduction to biopharmaceutics and pharmacokinetics -- Mathematical fundamentals in pharmacokinetics -- Biostatistics -- One-compartment open model : intravenous bolus administration -- Multicompartment models : intravenous bolus administration -- Intravenous infusion -- Drug elimination, clearance, and renal clearance -- Pharmacokinetics of oral absorption -- Multiple-dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Drug elimination and hepatic clearance -- Pharmacogenetics and drug metabolism -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design and in vitro drug product performance -- Drug product performance, in vivo : bioavailability and bioequivalence -- Biopharmaceutical aspects of the active pharmaceutical ingredient and pharmaceutical equivalence -- Impact of biopharmaceutics on drug product quality and clinical efficacy -- Modified-release drug products and drug devices -- Targeted drug delivery systems and biotechnological products -- Relationship between pharmacokinetics and pharmacodynamics -- Application of pharmacokinetics to clinical situations -- Application of pharmacokinetics to specific populations : geriatric, obese, and pediatric patients -- Dose adjustment in renal and hepatic disease -- Empirical models, mechanistic models, statistical moments, and noncompartmental analysis. |
| 520 3# - SUMMARY, ETC. |
|---|
| Summary, etc |
The landmark textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics-now fully updated. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical Term |
Biopharmaceutics. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical Term |
Pharmacokinetics. |
| 650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical Term |
Pharmacokinetics. |
| 650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical Term |
Biopharmaceutics. |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical Term |
Models, Chemical. |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical Term |
Drug Administration Routes. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Shargel, Leon, |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Yu, Andrew B. C., |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
Books |
