Applied biopharmaceutics & pharmacokinetics /
Edition statement:Seventh edition. Physical details: xvii, 910 pages : illustrations (some color) ; 24 cm ISBN:9780071830935 (hardcover : alk. paper); 0071830936 (hardcover : alk. paper); 9789814670241 (pbk.); 9814670243 (pbk.).| Item type | Current location | Call number | Status | Date due | Barcode |
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Books
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Reference Section (PUMHS Central Library) | 615.7 (Browse shelf) | Available | 38115 Ref |
Includes bibliographical references and index.
Introduction to biopharmaceutics and pharmacokinetics -- Mathematic fundamentals in pharmacokinetics -- Biostatistics -- One compartment open model : IV bolus injection -- Multicompartmental models : IV bolus injection -- Intravenous infusion -- Drug elimination and clearance -- Pharmacokinetics of oral absorption -- Multiple dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Renal and hepatic elimination of drugs -- Pharmacogenetics and drug metabolism -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design -- Drug product performance, in vivo : bioavailability and bioequivalence -- Biopharmaceutic aspects of the active pharmaceutical ingredient and pharmaceutical equivalence -- Impact of biopharmaceutics on drug product quality and clinical efficacy -- Modified release drug products and drug devices -- Targeted drug delivery systems and biotechnology products -- Relationship between pharmacokinetic and pharmacodynamics -- Application of pharmacokinetics in clinical situations -- Application of pharmacokinetics in specific populations -- Dosage adjustment in renal and hepatic disease -- Empirical models, mechanistic models, statistical moment and noncompartmental analysis.
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