Applied biopharmaceutics & pharmacokinetics /
by Shargel, Leon,(Acc.No:40017 Ref)
Series: 7th ed. Edition statement:Seventh edition. Physical details: xvii, 910 pages : illustrations ; ISBN:9780071830935; 0071830936; 9789814670241; 9814670243.| Item type | Current location | Call number | Copy number | Status | Date due | Barcode |
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Books
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Central Library, PUMHSW, Nawabshah (SBA) | 615.7 (Browse shelf) | 40017 Ref | Available |
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Introduction to biopharmaceutics and pharmacokinetics -- Mathematical fundamentals in pharmacokinetics -- Biostatistics -- One-compartment open model : intravenous bolus administration -- Multicompartment models : intravenous bolus administration -- Intravenous infusion -- Drug elimination, clearance, and renal clearance -- Pharmacokinetics of oral absorption -- Multiple-dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Drug elimination and hepatic clearance -- Pharmacogenetics and drug metabolism -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design and in vitro drug product performance -- Drug product performance, in vivo : bioavailability and bioequivalence -- Biopharmaceutical aspects of the active pharmaceutical ingredient and pharmaceutical equivalence -- Impact of biopharmaceutics on drug product quality and clinical efficacy -- Modified-release drug products and drug devices -- Targeted drug delivery systems and biotechnological products -- Relationship between pharmacokinetics and pharmacodynamics -- Application of pharmacokinetics to clinical situations -- Application of pharmacokinetics to specific populations : geriatric, obese, and pediatric patients -- Dose adjustment in renal and hepatic disease -- Empirical models, mechanistic models, statistical moments, and noncompartmental analysis.
The landmark textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics-now fully updated.
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